Liver support combos: which one should you buy?

How to choose a combination supplement

• Actual silymarin amount — Calculate extract mg × standardization % (e.g. 300 mg × 80% = 240 mg). 200–400 mg a day is the studied dose. Points off if no % is listed, since you can't know the real amount. Siliphos (phytosome) is an improved-absorption form, so 160–180 mg also counts
• Token ingredients — Points off for bragging about ingredient count, like '27-in-1', when most are 50 mg or less. If silymarin is sufficient, the max is 'Depends on your needs'; if silymarin is unknown or too low, 'Not recommended'. Amounts far below a studied dose, like 12 mg choline, are also flagged
• Hidden amounts — 'Not recommended' if a key ingredient promoted in the title — like milk thistle, NAC or TUDCA — is hidden in a 'Proprietary Blend'. If only minor ingredients are hidden, it's noted in the reasons
• Upper limits and cautions — Zinc 30 mg or more (upper limit 40 mg) and selenium 200 mcg (upper limit 400 mcg): add up with your other supplements. Berberine: caution with diabetes drugs and immunosuppressants. Black pepper (piperine) can change how prescription drugs are absorbed, so it's flagged
• Compared with buying separately — If a combo has less of the key ingredient than a single product, or hides it, you're better off with an 80% standardized milk thistle plus whatever else you need, bought separately
• Cost per day — Price ÷ count × the label's daily serving (lowest if a range). Stored as a number only; no points added or taken off in the verdict
• Label check — Products we could not verify in the NIH DSLD label database get 'Depends on your needs' at best. 'Detox' or 'cleanse' wording, review counts, star ratings and brand are not used in the verdict — only the numbers on the label