Concerns›Heart, blood sugar & weight

Swelling & cold hands and feet

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Bottom line

For swelling & cold hands and feet, start with Diosmin, Gotu kola extract (Centella asiatica), Pycnogenol (French maritime pine bark extract). The first one to look at is Diosmin — 600 mg a day; Split between morning and evening (once a day for a 600 mg single-capsule product).

Supplements ranked for this concern

AWell researchedBSome evidenceCLimited evidence
#SupplementEvidenceWhenHow muchCaution
1 Diosmin
Helps firm up vein walls. It's used as a medicine in some countries, and many people notice relief from leg swelling, numbness and cramps fairly quickly.
B Split between morning and evening (once a day for a 600 mg single-capsule product) 600 mg a day As blood vessels widen, it can cause dizziness, headaches or stomach pain. Details
2 Gotu kola extract (Centella asiatica)
Supports vein and lymph circulation. Studies found less swelling in the hands, feet and calves, and smaller ankle size.
B Steadily, as directed on the label 100–500 mg of extract a day. Start at the low end. It can rarely raise liver enzymes, so avoid it if your liver is weak. Don't take it while pregnant or breastfeeding. Details
3 Pycnogenol (French maritime pine bark extract)
May increase blood flow and lower blood vessel inflammation. Often used for leg swelling and cold hands and feet.
B With or without food. If you take 2+ capsules, split between morning and evening. 100–200 mg a day (up to 400 mg) Stop right away if you bruise easily or blood vessels burst. Be careful if you have very low blood pressure. Details
4 Magnesium
Helps muscles contract and relax, so higher doses are used for leg cramps and spasms. Pairs well with vein circulation ingredients.
B After meals (if you take 2+ capsules, split them) 200–400 mg a day (elemental magnesium) If you get diarrhea, take less. If you have kidney disease, talk to your doctor. Compare products
5 Aged garlic extract
May reduce blood clots and support circulation. Many women say it helps with cold hands and feet.
B After meals. If you take several capsules, split between morning and evening. 2–4 capsules of 300 mg a day Livelier circulation can make it harder to sleep. Details
6 Grape seed extract
May tighten vein walls so less fluid leaks out, which can help with tight, swollen calves.
C Split into two doses, morning and evening 100–400 mg a day Make sure it's grape seed extract, not grape leaf extract. Details
7 Vitamin E
May reduce oxidative damage in small blood vessels. Tocopherols are sometimes added for numb or cold hands and feet.
C After a meal. Stop 3 days to 1 week before surgery. 400 IU a day or less High doses over a long time raise bleeding and bruising risk. Don't go over 400 IU combined with your multivitamin. Details
8 Iron
When cold hands and feet come with paleness, dark circles and dizziness, iron often makes a big difference.
C On an empty stomach (right after a meal if it upsets your stomach), apart from coffee and tea 12–20 mg for symptoms, upper limit about 40 mg Confirm anemia with a blood test and follow your doctor's dose. Too much can be toxic to the liver. Compare products

Medications to watch out for

If you take any medication, talk to your doctor or pharmacist before starting.

Blood thinners such as warfarin (Coumadin) and aspirinPycnogenol · Aged garlic · Vitamin EBleeding may be harder to stop. Talk to your doctor.
Blood pressure medicinePycnogenol · MagnesiumBlood pressure may drop further and make you dizzy.
Sleeping pills and sedativesGotu kola extractSedation and drowsiness may get stronger. Talk to your doctor.
Being treated for liver diseaseGotu kola extractThere are rare reports of raised liver enzymes. Talk to your doctor before taking it.
Quinolone and tetracycline antibiotics (such as ciprofloxacin and doxycycline)IronThey block each other's absorption. Take them 2–4 hours apart.
Being treated for kidney diseaseMagnesiumIt may build up in your body. Talk to your doctor before taking it.

Before supplements: daily habits

  1. 01"De-bloating" products like potassium or bromelain only help for a while. They don't fix the root cause.
  2. 02If you swell because you eat poorly, you may be low on protein (albumin). Start with regular meals.
  3. 03When you stand or sit for a long time, move your ankles and calves now and then.
  4. 04If your hands and feet are cold and pale and you get dizzy, get tested for anemia first.
  5. 05With vein circulation ingredients, many people notice a difference in about a month. For blood vessel recovery, take them steadily for about 6 months.

Product comparison

ProductFormPer servingCountCost per day
Magnesium Citrate 200 mg TabletsBest value
NOW Foods
Citrate400 mg250 Low Amazon →
Magnesium Bisglycinate Powder (Albion)Best value
NOW Foods
Bisglycinate powder (Albion)250 mg91 Low Amazon →
Magnesium Citrate Pure PowderBest value
NOW Foods
Citrate powder435 mg76 Low Amazon →
Natural CALM Magnesium Powder (Raspberry Lemon)Best value
Natural Vitality
Citrate (magnesium carbonate + citric acid, forms when mixed with water)325 mg100 Low Amazon →
Magnesium (Citrate) 100 mg
Life Extension
Citrate200 mg100 Low Amazon →
High Absorption Magnesium (Glycinate Lysinate Chelate)
Doctor's Best
Glycinate/lysinate chelate (Albion)200 mg240 Low Amazon →
Magnesium Citrate Veg Capsules
NOW Foods
Citrate400 mg240 Low Amazon →
Magnesium Glycinate 100 mg (Albion)
NOW Foods
Bisglycinate chelate (Albion)200 mg180 Average Amazon →

Compare all Magnesium products →

Cost per day is relative — compared with other products of the same supplement. Check Amazon for the current price. Some links are affiliate links.

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