High blood pressure
Check what applies to you and the best-matched supplements move to the top.
Nothing checked yetDefault order, by strength of evidence.
Bottom line
For high blood pressure, start with Omega-3, Pycnogenol (French maritime pine bark extract), Coenzyme Q10 (CoQ10). The first one to look at is Omega-3 — 1,000 mg for maintenance, 2,000–3,000 mg for a stronger approach (EPA+DHA combined); Right after a meal. If you take 2+ capsules, split them across meals.
Supplements ranked for this concern
AWell researchedBSome evidenceCLimited evidence
| # | Supplement | Evidence | When | How much | Caution | |
|---|---|---|---|---|---|---|
| 1 | Omega-3Matches your checks Helps keep blood vessels flexible and supports circulation and triglyceride levels. A foundation for blood vessel care. |
A | Right after a meal. If you take 2+ capsules, split them across meals. | 1,000 mg for maintenance, 2,000–3,000 mg for a stronger approach (EPA+DHA combined) | If you have an irregular heartbeat, stay under 3,000 mg a day. With blood pressure medicine, watch for dizziness. | Compare products |
| 2 | Pycnogenol (French maritime pine bark extract)Matches your checks Many studies suggest it supports the inner lining of blood vessels, helping them widen, and may help with blood pressure. |
A | With or without food. If you take 2+ capsules, morning and evening. | Usually 100 mg a day (start at 100–200 mg, up to 400 mg) | Be careful if you have low blood pressure. If your readings go over 150–160, medicine comes first, not supplements. | Details |
| 3 | Coenzyme Q10 (CoQ10)Matches your checks Supports heart energy and helps blood vessels relax, which may help with systolic (top number) blood pressure. |
A | After breakfast or lunch (at night it can disturb sleep) | 100–200 mg a day. Split doses above 200 mg. | With blood pressure medicine, it may cause dizziness or headaches. Check your blood pressure often. | Compare products |
| 4 | Aged garlic extractMatches your checks May relax blood vessels and curb blood clots, which can help with blood pressure and cholesterol. |
A | After meals. If you take several capsules, split between morning and evening. | 2–4 capsules of 300 mg a day | If you take a blood thinner or aspirin, it may raise bleeding risk. Talk to your doctor. | Details |
| 5 | MagnesiumMatches your checks May help relax blood vessels and keep calcium from building up in them. |
B | After meals. If you take 2+ capsules, split them. | 200 mg for maintenance, 400 mg if you're low (start at 50–100 mg if you have low blood pressure) | If you have heart or kidney disease, talk to your doctor first. | Compare products |
| 6 | Vitamin K2Matches your checks Helps send calcium to your bones instead of your blood vessels, which may slow calcification of the arteries. |
B | Once a day, with a meal | 100–200 mcg a day (as MK-7) | If you take warfarin, it can affect how the drug works. Always talk to your doctor first. | Compare products |
| 7 | NattokinaseMatches your checks May break down blood clots and relax blood vessels, which can support circulation and blood pressure. |
B | On an empty stomach (1 hour before or 2 hours after a meal) | 2,000 FU a day as a baseline (2,000–6,000 FU) | Don't take it with blood thinners or aspirin. | Details |
| 8 | L-arginineMatches your checks Raises nitric oxide to widen blood vessels and may lower blood pressure slightly. |
B | On an empty stomach or between meals, during the day rather than at night | 1 g for maintenance. Blood pressure studies used 3–6 g. | Avoid it if you have low blood pressure or take erectile dysfunction medicine. | Details |
Medications to watch out for
If you take any medication, talk to your doctor or pharmacist before starting.
Blood thinners such as warfarin (Coumadin)Omega-3 · Pycnogenol · Aged garlic · NattokinaseTheir anti-clotting effects add up and may raise bleeding risk.
Warfarin (Coumadin)Vitamin K2It can affect how the drug works. Always talk to your doctor before taking it.
Antiplatelet drugs such as aspirinNattokinase · Omega-3 · PycnogenolBruising and bleeding such as nosebleeds may increase. Talk to your doctor before taking high doses.
Blood pressure medicineCoQ10 · Magnesium · Pycnogenol · L-arginineBlood pressure may drop further and make you dizzy. Don't cut back on your medicine on your own.
Erectile dysfunction drugs such as sildenafil (Viagra)L-arginineBoth widen blood vessels, so blood pressure may drop too low. Don't take them together.
Being treated for kidney diseaseMagnesiumMagnesium may build up in your body. Talk to your doctor first.
Before supplements: daily habits
- 01Cutting back on salty food and eating out is the most direct way to help your blood pressure.
- 02Measure your blood pressure at the same times each morning and evening, and keep a log.
- 03Stacking several blood-pressure-lowering supplements can cause dizziness or headaches. Add one at a time.
- 04Eat polyphenol-rich foods like olive oil, green tea and onions often.
- 05Supplements can't replace medicine. If your readings are high, see a doctor first.
Product comparison
| Product | Form | Per serving | Count | Cost per day | |
|---|---|---|---|---|---|
| Burp Less Ultra Omega-3 from Fish Oil 1400 mgBest value Nature Made |
EE (ethyl ester), enteric-coated | 935 mg | 90 | Low | Amazon → |
| Triple Strength Omega-3 950 mg Solgar |
EE (ethyl ester) | 882 mg | 100 | Low | Amazon → |
| Triple Strength Omega-3 Fish Oil 2400 mg, Lemon Nature's Branch |
Form not listed, lemon flavor | 1440 mg | 180 | Low | Amazon → |
| Extra-Strength Omega-3 Fish Oil 1000 mg + Vitamin E, Lemon NatureWise |
EE (ethyl ester), lemon flavor | 1000 mg | 60 | Low | Amazon → |
| Triple Strength Omega-3 Fish Oil 1250 mg (Wild Alaska Pollock) Sports Research |
rTG (re-esterified triglyceride) | 950 mg | 90 | Average | Amazon → |
| Triple Strength Omega-3 Fish Oil 2000 mg Dr. Tobias |
Form not listed, enteric-coated | 1400 mg | 180 | Average | Amazon → |
| Burp Less Omega-3 Fish Oil 1400 mg Minis Nature Made |
EE (ethyl ester), mini softgels | 930 mg | 60 | Average | Amazon → |
| Triple Strength Omega-3 Fish Oil 3000 mg, Lemon BioSchwartz |
Form not listed, lemon flavor | 2100 mg | 90 | Average | Amazon → |
Compare all Omega-3 products →
| Product | Form | Per serving | Count | Cost per day | |
|---|---|---|---|---|---|
| Co Q-10 100 mg (Q-Sorb) Rapid Release SoftgelsBest value Puritan's Pride |
Water-soluble Q-Sorb ubiquinone in rice bran oil softgels | 100 mg | 240 | Low | Amazon → |
| CoQ10 100 mg Vegetarian Capsules Nutricost |
CoQ10 powder with rice flour in veggie capsules | 100 mg | 120 | Low | Amazon → |
| CoQ10 100 mg Softgels NOW Foods |
Ubiquinone in olive oil softgels | 100 mg | 150 | Low | Amazon → |
| CoQ10 100 mg Softgels Nature Made |
Ubiquinone in soybean oil softgels | 100 mg | 120 | Low | Amazon → |
| Ultra CoQ10 100 mg Softgels Qunol |
Water-soluble ubiquinone (USP-grade) in MCT softgels | 100 mg | 120 | Average | Amazon → |
| Mega CoQ10 Ubiquinol 100 mg Softgels Qunol |
Ubiquinol (Kaneka) in MCT softgels | 100 mg | 100 | Average | Amazon → |
| Ubiquinol 100 mg Softgels Qunol |
Ubiquinol (Kaneka) in MCT softgels | 100 mg | 120 | Average | Amazon → |
| CoQ10 200 mg Softgels Nature Made |
Ubiquinone in soybean oil softgels | 200 mg | 105 | Average | Amazon → |
Compare all Coenzyme Q10 (CoQ10) products →
| Product | Form | Per serving | Count | Cost per day | |
|---|---|---|---|---|---|
| Magnesium Citrate 200 mg TabletsBest value NOW Foods |
Citrate | 400 mg | 250 | Low | Amazon → |
| Magnesium Bisglycinate Powder (Albion)Best value NOW Foods |
Bisglycinate powder (Albion) | 250 mg | 91 | Low | Amazon → |
| Magnesium Citrate Pure PowderBest value NOW Foods |
Citrate powder | 435 mg | 76 | Low | Amazon → |
| Natural CALM Magnesium Powder (Raspberry Lemon)Best value Natural Vitality |
Citrate (magnesium carbonate + citric acid, forms when mixed with water) | 325 mg | 100 | Low | Amazon → |
| Magnesium (Citrate) 100 mg Life Extension |
Citrate | 200 mg | 100 | Low | Amazon → |
| High Absorption Magnesium (Glycinate Lysinate Chelate) Doctor's Best |
Glycinate/lysinate chelate (Albion) | 200 mg | 240 | Low | Amazon → |
| Magnesium Citrate Veg Capsules NOW Foods |
Citrate | 400 mg | 240 | Low | Amazon → |
| Magnesium Glycinate 100 mg (Albion) NOW Foods |
Bisglycinate chelate (Albion) | 200 mg | 180 | Average | Amazon → |
Compare all Magnesium products →
| Product | Form | Per serving | Count | Cost per day | |
|---|---|---|---|---|---|
| Vitamin K2 MK-7 100 mcg SoftgelsBest value Nutricost |
MK-7 in sunflower oil softgels | 1 softgel: MK-7 100 mcg | 240 | Low | Amazon → |
| Vitamin D3 + K2 MK-7 5,000 IU Softgels Micro Ingredients |
D3 + MK-7 softgels | 1 softgel: D3 5,000 IU + MK-7 100 mcg | 300 | Low | Amazon → |
| Vitamin K2 MK-7 100 mcg Tablets Bronson |
MK-7 tablets | 1 tablet: MK-7 100 mcg | 120 | Low | Amazon → |
| Vitamin K2 MK-7 100 mcg Capsules Bronson |
MK-7 capsules | 1 capsule: MK-7 100 mcg | 120 | Low | Amazon → |
| Vitamin D3 + K2 (5000 IU D3 / 100 mcg MK-7) Softgels Nutricost |
D3 + MK-7 in sunflower oil softgels | 1 softgel: D3 5,000 IU + MK-7 100 mcg | 120 | Low | Amazon → |
| Vitamin K2 (MK-7) + D3 2-in-1 Complex Capsules Bronson |
D3 + MK-7 capsules | 1 capsule: D3 5,000 IU + MK-7 90 mcg | 120 | Low | Amazon → |
| MK-7 Vitamin K-2 100 mcg Veg Capsules NOW Foods |
MK-7 (MenaQ7) in plant-based capsules | 1 capsule: MK-7 100 mcg | 120 | Average | Amazon → |
| Mega D-3 5000 IU & MK-7 180 mcg Capsules NOW Foods |
D3 + MK-7 (MenaQ7) in plant-based capsules | 1 capsule: D3 5,000 IU + MK-7 180 mcg | 120 | Average | Amazon → |
Compare all Vitamin K2 products →
Cost per day is relative — compared with other products of the same supplement. Check Amazon for the current price. Some links are affiliate links.