Concerns›Energy, sleep & stress

Brain fog & memory

Check what applies to you and the best-matched supplements move to the top.

Nothing checked yetDefault order, by strength of evidence.

Bottom line

For brain fog & memory, start with Omega-3, Ginkgo biloba extract, Choline (Alpha-GPC, citicoline). The first one to look at is Omega-3 — 1,000 mg of EPA+DHA a day, 2,000 mg for a stronger approach; Right after a meal. If you take 2+ capsules, split them.

Supplements ranked for this concern

AWell researchedBSome evidenceCLimited evidence
#SupplementEvidenceWhenHow muchCaution
1 Omega-3
DHA is a building block of brain cell membranes. It's one of the few brain supplements with some evidence, so it's a basic pick.
A Right after a meal. If you take 2+ capsules, split them. 1,000 mg of EPA+DHA a day, 2,000 mg for a stronger approach If you take a blood thinner or get dizziness or nosebleeds, talk to your doctor. Compare products
2 Ginkgo biloba extract
Supports blood flow to the brain. Often used when forgetfulness comes with ringing in the ears or dizziness.
B Steadily, as directed on the product As directed on the label (choose a standardized product) It thins the blood, so avoid it if you take a blood thinner or aspirin. Details
3 Choline (Alpha-GPC, citicoline)
A raw material for acetylcholine, the brain chemical behind memory. Added after 50, when memory decline is more noticeable.
B Every day, steadily As directed on the label Rarely causes headaches or mood changes. Details
4 B-complex vitamins
Low B1 or B12 can weaken memory. Products with a form of B1 that reaches the brain well (fursultiamine) are popular.
B After breakfast or lunch (at night it can disturb sleep) 1 capsule of a product with 20–50 mg of each main B vitamin (total B6 100 mg or less) If you have gout, avoid products with high-dose B3 (niacin). Compare products
5 Magnesium (L-threonate)
Studies suggest the threonate form, which reaches the brain well, may help memory. It also supports stress and sleep.
C After dinner 1,500–2,000 mg a day as magnesium L-threonate (compound weight) Threonate is for adults. If you have kidney disease, talk to your doctor first. Compare products
6 Phosphatidylserine (PS)
A building block of brain cell membranes used for memory, but the more it's studied the less clear the benefit looks. Add it after the basics.
C Every day, steadily, rather than at a set time As directed on the label If you take dementia medicine, talk to the doctor who prescribed it. Details
7 Curcumin
Being studied for protecting brain blood vessels through anti-inflammatory and antioxidant action. Sometimes added when there's a family history of dementia.
C After meals, split between morning and evening An enhanced-absorption form (for the brain, e.g. Longvida) at the label amount, up to 1 g a day If you take a blood thinner or have gallstones or liver disease, talk to your doctor first. Compare products

Medications to watch out for

If you take any medication, talk to your doctor or pharmacist before starting.

Blood thinners such as warfarin (Coumadin) and aspirinGinkgo · Omega-3 · CurcuminMay raise bleeding risk. Avoid ginkgo, and talk to your doctor about the others.
Blood pressure medicineOmega-3 · Ginkgo · MagnesiumBlood pressure may drop further and make you dizzy.
Dementia drugs such as donepezil (Aricept) and anticholinergicsPhosphatidylserineIt may affect choline-related action. Talk to the doctor who prescribed them.
Some psychiatric medicinesGinkgo · Curcumin (products with piperine)The drug's effect may get stronger or the way it's broken down may change. Talk to your doctor.
Diabetes drugsCurcuminBlood sugar may drop too low. Be especially careful if your medicine is being adjusted.

Before supplements: daily habits

  1. 01If your focus dropped suddenly, check first for low iron or low vitamin D.
  2. 02Often, just fixing sleep and stress makes your head feel clearer.
  3. 03A diet built around extra virgin olive oil and fish is good for the blood vessels in your brain.
  4. 04It's hard to tell for yourself if a memory supplement works. Set a trial period of a few months, then decide.
  5. 05Don't stack several circulation ingredients (ginkgo, omega-3, curcumin) at once.

Product comparison

ProductFormPer servingCountCost per day
Burp Less Ultra Omega-3 from Fish Oil 1400 mgBest value
Nature Made
EE (ethyl ester), enteric-coated935 mg90 Low Amazon →
Triple Strength Omega-3 950 mg
Solgar
EE (ethyl ester)882 mg100 Low Amazon →
Triple Strength Omega-3 Fish Oil 2400 mg, Lemon
Nature's Branch
Form not listed, lemon flavor1440 mg180 Low Amazon →
Extra-Strength Omega-3 Fish Oil 1000 mg + Vitamin E, Lemon
NatureWise
EE (ethyl ester), lemon flavor1000 mg60 Low Amazon →
Triple Strength Omega-3 Fish Oil 1250 mg (Wild Alaska Pollock)
Sports Research
rTG (re-esterified triglyceride)950 mg90 Average Amazon →
Triple Strength Omega-3 Fish Oil 2000 mg
Dr. Tobias
Form not listed, enteric-coated1400 mg180 Average Amazon →
Burp Less Omega-3 Fish Oil 1400 mg Minis
Nature Made
EE (ethyl ester), mini softgels930 mg60 Average Amazon →
Triple Strength Omega-3 Fish Oil 3000 mg, Lemon
BioSchwartz
Form not listed, lemon flavor2100 mg90 Average Amazon →

Compare all Omega-3 products →

Cost per day is relative — compared with other products of the same supplement. Check Amazon for the current price. Some links are affiliate links.

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