Concerns›Women

Menopause symptoms

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Bottom line

For menopause symptoms, start with Soy isoflavones, Black cohosh, Magnesium. The first one to look at is Soy isoflavones — Start with 1 capsule of 60 mg. If needed, add one at a time, up to 3–4 capsules.; Take daily, then on and off once symptoms settle.

Supplements ranked for this concern

AWell researchedBSome evidenceCLimited evidence
#SupplementEvidenceWhenHow muchCaution
1 Soy isoflavones
A mild plant estrogen that may gradually ease hot flashes, sleep problems and mood changes.
A Take daily, then on and off once symptoms settle Start with 1 capsule of 60 mg. If needed, add one at a time, up to 3–4 capsules. Don't take it if you're being treated for breast cancer or another hormone-related cancer. If you take hormone medicine, talk to your doctor. Details
2 Black cohosh
Among plant ingredients for menopause, it has some of the strongest evidence. Often used especially for severe hot flashes.
A As directed on the label. Watch closely how you feel during the first 2–3 months. Only the amount on the label. Don't increase it on your own. Rare cases of severe liver damage have been reported even at normal doses, so avoid it if your liver is weak. Stop right away if you notice fatigue or yellow skin or eyes. Details
3 Magnesium
Helps your body relax and may ease menopause hot flashes, sleep problems, a racing heart and mood changes.
B After dinner 200–400 mg a day (as elemental magnesium) If you have kidney disease, talk to your doctor first. Compare products
4 Calcium
When estrogen drops, bones weaken quickly. A large study found that postmenopausal women who took calcium with vitamin D had higher bone density.
A After meals, split between morning and evening 200–400 mg a day from supplements (avoid 1,000 mg+ long term) Avoid it if you're prone to kidney stones. Rather than calcium alone, take it with magnesium, D and K2. Compare products
5 Vitamin D
Helps your gut absorb calcium. It's at the center of the bone health combo with calcium, magnesium and K2.
B Right after breakfast or lunch Start at 4,000 IU for 3–6 months → maintain at 1,000–2,000 IU Keep your total, including multivitamins, at 4,000 IU a day or less. Compare products
6 Pycnogenol (French maritime pine bark)
Officially recognized in some countries for easing menopause symptoms. It supports circulation and may help ease hot flashes.
B With or without food. If you take 2 capsules, split between morning and evening. 100–200 mg a day If you take blood thinners or blood pressure medicine, talk to your doctor. Details
7 Omega-3
A study of 180 women found fewer hot flashes, and it's a basic for heart and blood vessel care after menopause.
B Right after a meal 1,000–2,000 mg EPA+DHA a day If you take a blood thinner, talk to your doctor first. Compare products
8 Lecithin
Helps calm an overstimulated nervous system. Paired with soy isoflavones and magnesium for hot flashes, a racing heart and sleep problems.
C After dinner or before bed 5–10 g a day (1 tablespoon of granules is about 10 g) Some people find it keeps them awake. If you take a blood thinner, talk to your doctor. Details

Medications to watch out for

If you take any medication, talk to your doctor or pharmacist before starting.

Being treated for breast cancer or another hormone-related cancerSoy isoflavonesIt acts on estrogen receptors, so it's best not to take it.
Estrogen medicines (hormone therapy)Soy isoflavonesThey act on the same receptors. Talk to your doctor.
AntidepressantsBlack cohoshSerotonin effects may overlap. Talk to your doctor first.
Blood thinners such as warfarin (Coumadin) and aspirinOmega-3 · Pycnogenol · LecithinMay affect bleeding or clotting. Talk to your doctor.
Blood pressure medicinePycnogenol · Lecithin · Magnesium · Omega-3May lower blood pressure further and make you dizzy.
Osteoporosis drugs and thyroid medicineCalciumCalcium can sharply reduce how much of the drug you absorb. Take the drug first and calcium at least 1–2 hours later.

Before supplements: daily habits

  1. 01Salty food pulls calcium from your bones. During menopause, go easy on salt.
  2. 02Weight-bearing exercise like walking and strength training is good for both your bones and your mood.
  3. 03If symptoms are severe, ask your doctor first whether hormone therapy is an option. If it isn't, use supplements as a support.
  4. 04Caffeine and alcohol can worsen hot flashes and sleep, so try cutting back in the afternoon.
  5. 05Don't start several supplements at once. Add one at a time and see how your body responds.

Product comparison

ProductFormPer servingCountCost per day
Magnesium Citrate 200 mg TabletsBest value
NOW Foods
Citrate400 mg250 Low Amazon →
Magnesium Bisglycinate Powder (Albion)Best value
NOW Foods
Bisglycinate powder (Albion)250 mg91 Low Amazon →
Magnesium Citrate Pure PowderBest value
NOW Foods
Citrate powder435 mg76 Low Amazon →
Natural CALM Magnesium Powder (Raspberry Lemon)Best value
Natural Vitality
Citrate (magnesium carbonate + citric acid, forms when mixed with water)325 mg100 Low Amazon →
Magnesium (Citrate) 100 mg
Life Extension
Citrate200 mg100 Low Amazon →
High Absorption Magnesium (Glycinate Lysinate Chelate)
Doctor's Best
Glycinate/lysinate chelate (Albion)200 mg240 Low Amazon →
Magnesium Citrate Veg Capsules
NOW Foods
Citrate400 mg240 Low Amazon →
Magnesium Glycinate 100 mg (Albion)
NOW Foods
Bisglycinate chelate (Albion)200 mg180 Average Amazon →

Compare all Magnesium products →

Cost per day is relative — compared with other products of the same supplement. Check Amazon for the current price. Some links are affiliate links.

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